Examples of using Glucuronidation in English and their translations into Croatian
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The main metabolic pathway is glucuronidation of entacapone and its active metabolite,
Vemurafenib should be used with caution in combination with potent inhibitors of CYP3A4, glucuronidation and/or transport proteins e.g. ritonavir,
as an antiretroviral agent induces glucuronidation and as a result is expected to decrease the plasma concentrations of atovaquone.
The main metabolic processes are demethylenation and glucuronidation, although precise identification of the enzymes involved has not yet been achieved.
Your doctor must treat you with caution if you have a glucuronidation disorder like Gilbert's syndrome.
Clinically significant drug interactions involving glucuronidation are not anticipated due to limited contribution of individual UGT enzymes in the glucuronidation of eltrombopag.
Patients with deficient glucuronidation of bilirubin, such as those with Gilbert's syndrome,
Based on a human study with radiolabelled eltrombopag, glucuronidation plays a minor role in the metabolism of eltrombopag.
Aromatic and aliphatic hydroxylation or glucuronidation metabolites are present in very low levels,
4-hydroxyospemifene inhibited glucuronidation mainly via UGT1A3
is extensively metabolised by cytochrome P450 and subsequent glucuronidation.
with subsequent phase II reactions of sulphation and glucuronidation.
Aromatic and aliphatic hydroxylation or glucuronidation metabolites are present in very low levels,
Medicinal products that inhibit glucuronidation, such as NSAIDs
Based on preclinical data, it is suggested that tafamidis is metabolised by glucuronidation and excreted via the bile.
Oxidation by CYP3A and glucuronidation by UGT2B7 appear to be the major pathways of cobimetinib metabolism.
CYP3A4 and glucuronidation, aprepitant can decrease plasma concentrations of substrates eliminated by these routes within two weeks following initiation and treatment.
Zidovudine 200 q8h 300 q6h Zidovudine↓ 25% ND Ritonavir may induce the glucuronidation of zidovudine, resulting in slightly decreased levels of zidovudine.
administered 1 hour before intramuscular lorazepam 2 mg(metabolised by glucuronidation), the pharmacokinetics of both medicines were unchanged.
suggesting that sulfation and glucuronidation do not appear to be major pathways involved in the excretion of temsirolimus.