Examples of using Glucuronidation in English and their translations into Swedish
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Medicine
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Colloquial
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Ecclesiastic
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Ecclesiastic
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Official/political
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Computer
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Political
a mild inducer of CYP3A4 and glucuronidation, aprepitant can decrease plasma concentrations of substrates eliminated by these routes.
hydroxylation with subsequent glucuronidation) account for approximately 23%,
Vemurafenib should be used with caution in combination with potent inhibitors of CYP3A4, glucuronidation and/or transport proteins e.g. ritonavir,
Based on a human study with radiolabelled eltrombopag, glucuronidation plays a minor role in the metabolism of eltrombopag.
Ritonavir may induce the glucuronidation of zidovudine, resulting in slightly decreased levels of zidovudine.
In vitro studies suggest that CYP3A4 metabolism and glucuronidation are responsible for the metabolism of vemurafenib.
Valproate, which inhibits the glucuronidation of lamotrigine, reduces the metabolism of lamotrigine
a metabolising process called glucuronidation e.g. rifampicin,
catalysed the acyl glucuronidation.
simvastatin acid by 1.9-fold, possibly due to inhibition of the glucuronidation pathway see sections 4.2 and 4.4.
UGT1A8 may potentially affect the glucuronidation of ospemifene and/or 4-hydroxyospemifene.
Zidovudine 200 q8h 300 q6h Zidovudine↓ 25% ND Ritonavir may induce the glucuronidation of zidovudine, resulting in slightly decreased levels of zidovudine.
Clinically significant drug interactions involving glucuronidation are not anticipated due to limited contribution of individual UGT enzymes in the glucuronidation of eltrombopag.
Oxidation by CYP3A and glucuronidation by UGT2B7 appear to be the major pathways of cobimetinib metabolism.
Your doctor must treat you with caution if you have a glucuronidation disorder like Gilbert's syndrome.
In vitro and in vivo data indicate that lumacaftor is mainly metabolised via oxidation and glucuronidation.
Induction As a moderate inducer of CYP2C9 and a mild inducer of CYP3A4 and glucuronidation, aprepitant can decrease plasma concentrations of substrates eliminated by these routes within two weeks following initiation of dosing regimen.
In women not already taking an inducer of lamotrigine glucuronidation and taking a hormonal contraceptive that includes one week of inactive treatment(for example"pill-free week"),
most likely caused by an induction of glucuronidation, and an average increase of 31-35% in exposure to phenytoin,
Raltegravir is eliminated primarily by glucuronidation in the liver.