GLUCURONIDATION in Slovenian translation

• glukuronidacijo
• glukuronidacije
• glukuronidacija
• glukuronidacijske
• glukuronizacija
• glukoronidacijo

Examples of using Glucuronidation in English and their translations into Slovenian

Based on a human study with radiolabelled eltrombopag, glucuronidation plays a minor role in the metabolism of eltrombopag.
Na osnovi podatkov študije z radioaktivnim izotopom označenega eltrombopaga pri ljudeh je glukuronidacija manj pomembna za presnovo eltrombopaga.

CYP3A4 and glucuronidation.
CYP3A4 in glukuronidacije.

Interaction with indinavir/ ritonavir not studied Ritonavir induces oxidation by CYP2C9 and glucuronidation and as a result is expected to decrease the plasma concentrations of anticonvulsants.
Ritonavir inducira oksidacijo, ki jo povzroča CYP2C9, in glukuronidacijo, zato se pričakuje zmanjšanje koncentracij antikonvulzivov v plazmi.

Oxidation by CYP3A and glucuronidation by UGT2B7 appear to be the major pathways of cobimetinib metabolism.
Kot kaže, sta glavni poti presnove kobimetiniba oksidacija s CYP3A in glukuronidacija z UGT2B7.

which induce hepatic drug-metabolising enzymes induce the glucuronidation of lamotrigine and enhance the metabolism of lamotrigine.
inducirajo jetrne encime za presnovo zdravil, inducirajo glukuronidacijo lamotrigina in pospešijo njegovo presnovo.

induce lamotrigine glucuronidation are withdrawn.
pomembno ne zavirajo niti ne inducirajo glukuronidacije lamotrigina.

decreased lamotrigine half-life due to induction of the hepatic enzymes responsible for glucuronidation.
zmanjšal razpolovni čas lamotrigina zaradi indukcije jetrnih encimov odgovornih za glukuronidacijo.

Tween20 significantly inhibited chrysin glucuronidation.
Tween20 bistveno zavira chrysin glukuronidacijo.

induce lamotrigine glucuronidation are added.
pomembno ne zavirajo niti ne inducirajo glukuronidacije lamotrigina.

CYP3A4 and glucuronidation approximately one week after treatment.
CYP3A4 in glukuronidacije približno en teden po zdravljenju.

Based on preclinical data, it is suggested that tafamidis is metabolised by glucuronidation and excreted via the bile.
Na osnovi predkliničnih podatkov se domneva, da se tafamidis presnavlja z glukuronidacijo in izloča z žolčem.

Biotransformation of diclofenac takes place partly by glucuronidation of the intact molecule,
Presnova diklofenak se doseže delno z glukuronidacijo nemodificirani molekulo,

Vemurafenib should be used with caution in combination with potent inhibitors of CYP3A4, glucuronidation and/or transport proteins(e.g. ritonavir,
Vemurafenib je treba uporabljati previdno v kombinaciji z močnimi inhibitorji CYP3A4, glukuronidacije in/ali prenašalnih beljakovin(npr. ritonavirjem,

Studies in humans and in vitro studies using human liver microsomes have demonstrated that efavirenz is principally metabolised by the CYP system to hydroxylated metabolites with subsequent glucuronidation of these hydroxylated metabolites.
Študije pri ljudeh in študije in vitro z uporabo človeških jetrnih mikrosomov so pokazale, da se efavirenz presnavlja predvsem s sistemom CYP, in sicer v hidroksilirane presnovke, z nadaljnjo glukuronidacijo teh hidroksiliranih presnovkov.

direct glucuronidation; direct sulfation;
direktna glukuronidacija; direktna sulfatacija;

Induction As a moderate inducer of CYP2C9 and a mild inducer of CYP3A4 and glucuronidation, aprepitant can decrease plasma concentrations of substrates eliminated by these routes within two weeks following initiation of dosing regimen.
Indukcija Kot zmerni induktor CYP2C9 ter blagi induktor CYP3A4 in glukuronidacije, lahko aprepitant v dveh tednih po začetku zdravljenja zniža plazemske koncentracije substratov, ki se izločajo po teh poteh.

CYP2C9 isoenzymes and glucuronidation(about 20%) of the sulfonamide moiety.
CYP2C9 citokroma P450 ter glukuronidacijo(približno 20%) sulfonamidne skupine.

Aromatic and aliphatic hydroxylation or glucuronidation metabolites are present in very low levels,
Aromatski in alifatski presnovki hidroksilacije ali presnovki glukuronidacije so prisotni v zelo nizkih ravneh,

suggesting that sulfation and glucuronidation do not appear to be major pathways involved in the excretion of temsirolimus.
glukuronidnih konjugatov, kar kaže na to, da sulfatacija in glukuronidacija nista pomembni poti, vpleteni v izločanje temsirolimusa.

Biotransformation: studies in humans and in vitro studies using human liver microsomes have demonstrated that efavirenz is principally metabolised by the cytochrome P450 system to hydroxylated metabolites with subsequent glucuronidation of these hydroxylated metabolites.
Presnova: študije pri ljudeh in študije in vitro z uporabo človeških jetrnih mikrosomov so pokazale, da se efavirenz presnavlja predvsem s sistemom citokroma P450, in sicer v hidroksilirane presnovke, z nadaljnjo glukuronidacijo teh hidroksiliranih presnovkov.