Examples of using Glucuronidation in English and their translations into Portuguese
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Medicine
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Ecclesiastic
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Ecclesiastic
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Computer
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Official/political
Glucuronidation disorder like Gilbert's syndrome.
Concentrations may be reduced due to increased glucuronidation by Kaletra.
This is a glucuronidation reaction.
Glucuronidation and renal excretion are the main mechanisms of elimination in CYP2D6 poor metabolisers.
The main metabolic processes are demethylenation and glucuronidation, although precise identification of the enzymes involved has not yet been achieved.
Monitoring of serum uric acid is therefore recommended 1-2 weeks after start of treatment with a potent inducer of glucuronidation.
Interaction with indinavir/ ritonavir not studied Ritonavir induces glucuronidation and as a result is expected to decrease the plasma concentrations of atovaquone.
Metabolic pathways of vismodegib in humans include oxidation, glucuronidation, and an uncommon pyridine ring cleavage.
Adjunctive therapy WITHOUT valproate and WITHOUT inducers of lamotrigine glucuronidation see section 4.5.
Interaction with indinavir/ ritonavir not studied Ritonavir induces oxidation by CYP2C9 and glucuronidation and as a result is expected to decrease the plasma concentrations of anticonvulsants.
Carvedilol is metabolized primarily by glucuronidation and by cyp2d6 to hidroxifenilcarvedilol and cyp2c9 to o-desmetilcarvedilol.
According to results of in vitro studies the metabolic pathway of atorvastatin via glucuronidation is inhibited by Gemfibrozil.
adjunctive therapy WITHOUT valproate and WITHOUT inducers of lamotrigine glucuronidation see section 4.5.
About 90% of paracetamol is conjugated in the liver glucuronidation- 40-67%; sulfation- 20-46%, forming inactive metabolites excreted in the urine.
with subsequent phase II reactions of sulphation and glucuronidation.
In studies with eslicarbazepine in fresh human hepatocytes a mild activation of UGT1A1 mediated glucuronidation was observed.
both drugs share glucuronidation as their main metabolic pathway.
Lamotrigine: Combined hormonal contraceptives have been shown to significantly decrease plasma concentrations of lamotrigine when coadministered likely due to induction of lamotrigine glucuronidation.
it is suggested that tafamidis is metabolised by glucuronidation and excreted via the bile.
UGT1A8 may potentially affect the glucuronidation of ospemifene and/or 4-hydroxyospemifene.