Examples of using Multiple dose in English and their translations into Croatian
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Computer
Pharmacokinetic modelling simulation analysis showed that Defitelio plasma concentrations do not accumulate upon multiple dose administration and with doses up to 4-fold the therapeutic dose. .
The potential effect of dabrafenib on QT prolongation was assessed in a dedicated multiple dose QT study.
There have been reports of bacterial keratitis associated with the use of multiple dose containers of topical ophthalmic products.
An open-label, multiple dose pharmacokinetic, safety and tolerability study in
With multiple dose administration(10 day-treatment at 50 mg riluzole bid),
Based on a multiple dose clinical trial in adults
Due to the lack of multiple dose PK data for piperaquine, administration of any strong CYP3A4-inhibitors should be discouraged after initiation(i.e. the first dose)
Randomised, double-blind, single and multiple dose, crossover studies in 204 healthy volunteers showed that the pharmacokinetic profile of Filgrastim HEXAL was comparable to that of the reference product after subcutaneous
Following both single dose(50 mg) and multiple dose(30 mg/m2 twice daily)
Following coadministration of multiple dose dulaglutide with steady state metformin(immediate release formula[IR]), metformin AUCτ increased up to 15%
The pharmacodynamic effects of Entresto were evaluated after single and multiple dose administrations in healthy subjects
naltrexone IR administered as single agents in the multiple dose setting i.e., under steady state conditions.
In a multiple dose clinical trial, in adults
The pharmacokinetics of Viramune prolonged-release has also been studied in a multiple dose pharmacokinetics study(study 1100.1489)
Clinical efficacy and safety In a multiple dose clinical trial, in which up to 20 mg
evaluated in a double-blind, randomised, multiple dose, phase III,
reduced tadalafil(40 mg once per day) systemic exposure by 42% and Cmax by 27% following multiple dose co-administration.
this difference was not observed after multiple dose administration.
Multiple dose administration of Quinsair 240 mg twice daily by inhalation results in levofloxacin systemic exposure approximately 50% lower than that observed following systemic administration of comparable doses see Table 3.
hepatic impairment to 9 controls, the single and multiple dose exposure of tipranavir and ritonavir were increased in patients with hepatic impairment