Examples of using Hydroxycarbamide in English and their translations into Hungarian
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Hydroxycarbamide(also called hydroxyurea), taken regularly,
Women of childbearing age receiving hydroxycarbamide should be advised to avoid becoming pregnant,
severe peripheral neuropathy have been reported in HIV-infected patients who received hydroxycarbamide in combination with antiretroviral medicinal products,
Hydroxycarbamide at 30, 100 and 300 µM is not metabolised in vitro by cytochrome P450s of human liver microsomes.
The yearly frequency of acute chest syndrome was also reduced by 25 to 33% under hydroxycarbamide in several studies.
Leg ulcers are a common complication of Sickle Cell Syndrome, but have also been reported in patients treated with hydroxycarbamide.
Long-term data on the continued use of hydroxycarbamide in patients with Sickle Cell Syndrome are available in children
Other known pharmacological effects of hydroxycarbamide which may contribute to its beneficial effects in Sickle Cell Syndrome include decrease of neutrophils,
Long-term data on the continued use of hydroxycarbamide in patients with Sickle Cell Syndrome are available in children
Recently, hydroxycarbamide has shown to be associated with the generation of nitric oxide suggesting that nitric oxide stimulates cyclic guanosine monophosphatase(cGMP)
Although the precise way that it works in this disease is not understood, hydroxycarbamide can reduce the numbers of cells that are circulating in the blood,
Because hydroxycarbamide is a well-known substance that is already used in other medicines,
Due to potentially severe clinical outcomes for the cutaneous vasculitic ulcers reported in patients with myeloproliferative disease, hydroxycarbamide should be discontinued and/or its dose reduced if cutaneous vasculitic ulcerations develop.
Concomitant use of hydroxycarbamide with a live virus vaccine may potentiate the replication of the vaccine virus and/or may increase the adverse reaction of the vaccine virus, because normal defence mechanisms may be suppressed by hydroxycarbamide therapy.
In the human, according to a retrospective analysis of a cohort of 123 adult patients treated with hydroxycarbamide, twenty-three pregnancies have been reported from 15 women treated with hydroxycarbamide and partners of 3 men treated with hydroxycarbamide.
An erythema caused by radiation therapy may be aggravated by hydroxycarbamide.
The specific mechanism of action of hydroxycarbamide is not fully understood.
Hydroxycarbamide is unequivocally genotoxic in a wide range of test systems.
Vaccination with a live vaccine in a patient taking hydroxycarbamide may result in severe infections.
In all clinical studies, there was a significant increase in HbF from baseline after hydroxycarbamide use.