Examples of using Methotrexate in English and their translations into Thai
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Increases blood concentration of penicillins, lithium preparations, digoxin and methotrexate;
Methotrexate: enhancing its side effects on the hematopoietic system;
In his presence, the free fractions of methotrexate can significantly increase.
When using anticoagulants, hypoglycemic agents and methotrexate, Biseptol increases their effectiveness;
Methotrexate can lower the immune response to vaccination with inactivated and live viral vaccines.
L-asparaginase: a decrease in the severity of the antitumor action of methotrexate;
Drugs that block tubular secretion(for example, probenecid): increased toxicity of methotrexate.
Methotrexate is a cytotoxic drug, so care should be taken when handling it.
Clinicians are also increasingly using other non-steroidal immune suppression medication such as Methotrexate, Hydroxochloroquine and Azithioprine.
Methotrexate: increased side effects from the hematopoietic system(risk of developing leukopenia and anemia);
Also, with its simultaneous use with the drug"Methotrexate", the negative effect on hematopoiesis increases.
Methotrexate: the likelihood of toxic effects from the hematopoietic system, the occurrence of leukopenia and anemia;
At simultaneous use with the drugs oppressing marrow(for example, methotrexate), development of cytopenia is possible.
A large amount of the drug increases the toxicity of methotrexate and reduces the effect of hypoglycemic drugs;
Methotrexate, probenicid and other drugs secreted in the renal tubules- reducing their excretion by the kidneys, reducing the effectiveness of furosemide;
The regimen should be prescribed by a physician experienced in the use of Methotrexate and familiar with its properties and action features.
This medication should not be used simultaneously with cyclophosphamide, chloral hydrate, methotrexate, petidine and 6-mercaptopurine, since Bellaspon enhances not only their effect, but also toxicity.
Methotrexate: enhancing its side effects on the hematopoietic system(risk of leukopenia and anemia, periodic monitoring of the complete blood count is shown);
Antibiotics poorly absorbed in the gastrointestinal tract(tetracyclines, chloramphenicol): reduced absorption of methotrexate and impaired metabolism due to the suppression of the normal intestinal microflora;
Medicamental therapy with the help of localChemotherapy with the use of cytostatic drugs, for example,"Cyclophosphamide". Application of"Ftoruracil" and"Methotrexate" can also be used.