LAPATINIB - oversættelse til Dansk

• lapatinib

Eksempler på brug af Lapatinib på Engelsk og deres oversættelser til Dansk

following intravenous hydration and interruption of treatment with lapatinib and letrozole.
afbrydelse af behandlingen med lapatinib og letrozol forsvandt symptomerne.

did not result in discontinuation of treatment with lapatinib.
resulterede ikke i afbrydelse af behandlingen med lapatinib.

If you are allergic(hypersensitive) to lapatinib or any of the other ingredients of Tyverb.
Hvis du er overfølsom(allergisk) over for lapatinib eller et af de øvrige indholdsstoffer i Tyverb.

Lapatinib should be taken either at least one hour before,
Lapatinib bør tages enten mindst en time før

The recommended dose of lapatinib is 1250 mg(i. e. five tablets) once daily continuously.
Den anbefalede dosis af lapatinib er 1250 mg(fem tabletter) en gang daglig.

In vitro studies indicate that lapatinib is a substrate for the transporters BCRP(ABCG1)
In vitro- forsøg indikerer, at lapatinib er et substrat for transportørerne BCRP(ABCG1)

improved in more than 60% of cases on discontinuation of treatment with lapatinib.
blev bedre i mere end 60% af tilfældene ved ophør af behandlingen med lapatinib.

Lapatinib retained significant activity against breast cancer cell lines selected for long-term growth in trastuzumab-containing medium in vitro.
Lapatinib bevarede betydelig aktivitet over for brystcancercellelinjer selekteret for langtidsvækst i trastuzumab- holdigt medium in vitro.

Coadministration of lapatinib with moderate inhibitors of CYP3A4 should proceed with caution
Indgift af lapatinib samtidig med moderate inhibitorer af CYP3A4 bør ske med forsigtighed,

Lapatinib dosing should be discontinued if changes in liver function are severe and patients should not be retreated.
Behandlingen med lapatinib bør afbrydes ved alvorlige ændringer i leverfunktionen, og behandlingen bør ikke genoptages hos disse patienter.

avoid becoming pregnant while receiving treatment with lapatinib.
undgå at blive gravide under behandlingen med lapatinib.

Tyverb should not be used in people who may be hypersensitive(allergic) to lapatinib or any of the other ingredients.
Tyverb bør ikke anvendes til patienter, der kan være overfølsomme(allergiske) over for lapatinib eller andre af indholdsstofferne.

Lapatinib inhibits CYP3A(Ki 0.6 to 2.3 µg/ ml)
Lapatinib hæmmer CYP3A(Ki 0, 6- 2, 3 µg/ ml) og CYP2C8(0, 3 µg/ ml)

Administration of lapatinib to patients with moderate to severe hepatic impairment should be undertaken with caution due to increased exposure to the medicinal product.
Indgift af lapatinib til patienter med moderat til svært nedsat leverfunktion bør ske med forsigtighed pga. øget optagelse af lægemidlet.

However, daily dosing of lapatinib results in achievement of steady state within 6 to 7 days,
Men daglig dosis af lapatinib resulterer i steady state i løbet af 6- 7 dage,

this had a similar incidence in both treatment groups lapatinib plus capecitabine.
denne havde den samme forekomst i begge grupper lapatinib plus capecitabine.

Coadministration of lapatinib with strong inhibitors of CYP3A4(e. g. ritonavir,
Indgift af lapatinib samtidig med stærke inhibitorer af CYP3A4(fx ritonavir,

Lapatinib is not significantly renally excreted and is highly bound to plasma proteins, therefore haemodialysis would not be expected to be an effective method to enhance the elimination of lapatinib.
Det kan derfor ikke forventes, at hæmodialyse vil være en effektiv måde at øge udskillelsen af lapatinib.

The efficacy and safety of lapatinib in combination with capecitabine in breast cancer patients with good performance status was evaluated in a randomized, phase III trial.
Effekten og sikkerheden ved lapatinib i kombination med capecitabine til brystcancerpatienter med god performance status blev evalueret i et randomiseret fase III- forsøg.

prior to initiation of treatment with lapatinib to ensure baseline LVEF was within the institutions normal limits.
initiering af behandling med lapatinib for at sikre, at baseline- LVEF lå inden for institutionens normale grænser.