Examples of using In vitro data in English and their translations into Slovenian
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Medicine
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In vitro data have shown that at therapeutic concentrations,
Based on in vitro data, riotsiguat and its main metabolite are found to be substrates for transport proteins P-gp(P-glycoprotein)
Based on in vitro data, cinacalcet is a strong inhibitor of CYP2D6,
In vitro data indicate that ceftolozane did not inhibit P-gp,
Based on in vitro data riociguat and its main metabolite are substrates of the transporter proteins P-gp(P-glycoprotein) and BCRP(breast cancer resistance protein).
In vitro data indicate that lipegfilgrastim is has little
You can use in vitro data to fully or partly fulfil information requirements that would otherwise need data to be generated with tests on living organisms(in vivo tests).
In vitro data indicate that neither tazobactam nor the tazobactam metabolite M1 inhibit P-gp, BCRP, OATP1B1, OATP1B3,
In vitro data indicate that ulipristal acetate
In vitro data indicated that idelalisib is not an inhibitor of the metabolising enzymes CYP1A2,
In vitro data show that CYP2C9, CYP2C19
In vitro data suggests that cysteamine bitartrate is likely to be metabolized by multiple CYP enzymes,
Although in vitro data suggest that efavirenz inhibits CYP2C9
In vitro data also indicated that tafamidis meglumine does not significantly inhibit cytochrome P450 enzymes CYP1A2,
Although in vitro data suggest that efavirenz inhibits CYP2C9
In vitro data from human liver microsomes indicate that cytochrome P450 enzymes CYP2D6
The Applicant stated that the presented in vitro data can be predictive of pharmacokinetic bioequivalence for Cmax
In vitro data in human kidney microsomes suggest that the kidney may be one of the major organs contributing to the hydrolysis of vildagliptin to its major inactive metabolite, LAY151.
a number of Member States did not consider the product to be approvable based on the submitted in vitro data only.
In vitro data showed no difference in plasma protein binding in plasma samples of healthy subjects and hepatically impaired(mild,