Примери за използване на Multiple dosing на Английски и техните преводи на Български
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Multiple dosing of 7,200 mg/day was associated with no major signs or symptoms.
Upon multiple dosing, plasma concentrations of bosentan decrease gradually to 50-65% of those seen after single dose administration.
Tmax being approximately 1-2 hrs after single and multiple dosing.
Similar CST½ values were observed following both single and repeated administration, demonstrating that there is a predictable and consistent duration of action after multiple dosing of the sublingual tablet.
which is in line with the accumulation observed after multiple dosing.
accumulate more upon multiple dosing than does AsIII.
Asian breast cancer patients after multiple dosing.
Multiple dosing has no effect on the pharmacokinetics of either imipenem
Similar CST½ values were observed following both single and repeated administration demonstrating that there is a predictable and consistent duration of action after multiple dosing of the sublingual tablet.
the absence of autoinduction upon multiple dosing in patients indicates that cinacalcet is not an inducer of CYP3A4,
After multiple dosing with cannabidiol, the 7-OH-CBD metabolite(active in a preclinical model of seizure)
the absence of auto- induction upon multiple dosing in patients indicates that cinacalcet is not an inducer of CYP3A4,
Because nevirapine induces its own metabolism with multiple dosing, this single dose study may not reflect the impact of hepatic impairment on multiple dose pharmacokinetics see section.
After multiple dosing of 150 to 200 mg every two weeks,
little increase in Cmax or AUC is expected upon multiple dosing in the clinical setting.
are designed for multiple dosing using an electronic injection device that delivers 8.8, 22 or 44 micrograms per dose. .
Following multiple dosing, the increase in ataluren
to 42-64 mL/kg after multiple dosing(48-192 IU/kg), respectively.
Following multiple dosing in patients, modified-release levodopa/carbidopa had reduced fluctuations in levodopa plasma concentrations with peak-to-trough fluctuation index of 1.5 with minimal accumulation of levodopa.
are dose proportional and predictable with single and multiple dosing and this simple and quick to administer formulation therefore fulfils an unmet need for a product indicated for the treatment of breakthrough pain in cancer patients.