Examples of using Antithrombin in English and their translations into Romanian
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The therapeutic goal of treatment with antithrombin alfa is to increase to,
The half-life of recombinant antithrombin may be altered with concomitant treatment with these anticoagulants due to an altered antithrombin turnover.
Your health care provider will prepare a solution of antithrombin alfa to be administered to you through your vein.
The active substance in ATryn, antithrombin alfa, is a copy of the natural blood protein that is produced by recombinant DNA technology.
Therefore, it is important that your antithrombin blood level be maintained at sufficient levels in these situations.
In the body, antithrombin blocks thrombin,
of antithrombin activity is equivalent to that quantity of antithrombin in one ml of normal human plasma.
If you have an inborn deficiency of antithrombin, your blood level of antithrombin is lower than normal.
The product contains approximately 175 IU/ ml antithrombin alfa when reconstituted with 10 ml of Sterile Water for Injection(WFI).
The number of units of antithrombin alfa administered is expressed in International Units(IU), which is related to the current WHO standard for antithrombin concentrate.
Initial treatment starts with a loading dose targeting an antithrombin activity level of 100%.
Antithrombin alfa is a recombinant form of human antithrombin and is produced by recombinant DNA technology in the milk of transgenic goats.
This medicine is used in patients who have‘congenital antithrombin deficiency'(inherited low levels of the protein antithrombin).
Frequent antithrombin activity assessments and dosing adjustments may be necessary when starting treatment and just after surgery.
No antibodies to antithrombin alfa have been detected up to 90 days following treatment with ATryn.
Your treatment will be initiated under the supervision of a physician experienced in the care of patients with an inborn deficiency of antithrombin.
Antithrombin activity is greatly enhanced by heparin and the anticoagulant effects of heparin depend on the presence of antithrombin.
Each vial of ATryn contains a lyophilised powder of 1750 IU antithrombin alfa and is intended for single use only.
containing the active substance antithrombin alfa.
The calculation of the required dosage of antithrombin alfa is based on pre-treatment plasma antithrombin activity and body weight.