Examples of using Lenalidomide in English and their translations into Slovenian
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including both lenalidomide and bortezomib, and whose disease progressed after the last treatment.
In mantle cell lymphoma patients, lenalidomide is associated with a higher incidence of grade 3
In myelodysplastic syndromes patients, lenalidomide is associated with a higher incidence of grade 3
All treatment-emergent adverse events with≥ 5% of subjects in lenalidomide arm and at least 2% difference in proportion between lenalidomide and control arm.
older who received lenalidomide, there was a higher incidence of serious adverse reactions
at least 1.0% difference in proportion between lenalidomide and control arm.
in which 148 patients received lenalidomide at a dose of 10 mg,
KRd= Kyprolis, lenalidomide and dexamethasone; Rd= lenalidomide, dexamethasone; PFS= progression-free survival;
Lenalidomide is present in human semen(<
should be used with caution in multiple myeloma patients receiving lenalidomide with dexamethasone(see sections 4.4 and 4.8).
early deaths in the lenalidomide arm and 2/28(7%)
Results from human in vitro metabolism studies indicate that lenalidomide is not metabolised by cytochrome P450 enzymes suggesting that administration of lenalidomide with drugs that inhibit cytochrome P450 enzymes is not likely to result in metabolic drug interactions in man.
Digoxin Concomitant administration with lenalidomide 10 mg/day increased the plasma exposure of digoxin(0.5 mg,
Results from human in vitro metabolism studies indicate that lenalidomide is not metabolised by cytochrome P450 enzymes suggesting that administration of lenalidomide with medicinal products that inhibit cytochrome P450 enzymes is not likely to result in metabolic medicinal product interactions in humans.
Return to≥ 0.5 x 109/L Resume lenalidomide at next lower dose level once daily. ªIf the subject has not been receiving G-CSF therapy,
Second Primary Malignancies are known to be associated with lenalidomide exposure which was extended in patients treated with Empliciti combined with lenalidomide
SPMs are known to be associated with lenalidomide exposure, which was extended in patients treated with Empliciti combined with lenalidomide
In the Phase III study, 69 patients were on lenalidomide 5 mg, 69 patients on lenalidomide 10 mg
Cases of viral reactivation have been reported in patients receiving lenalidomide, including serious cases of herpes zoster or hepatitis B virus(HBV) reactivation.
As Kyprolis is given in combination with lenalidomide, you must follow the Pregnancy Prevention Programme(see package leaflet for lenalidomide for information on pregnancy prevention