Примери за използване на Maximum tolerated на Английски и техните преводи на Български
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The goal of this study is to identify the maximum tolerated dose(MTD) of the medication under investigation.
The maximum tolerated dose of Tarceva in NSCLC patients who currently smoke cigarettes was 300 mg.
8 of a 21 day cycle without reaching a maximum tolerated dose.
female rats up to the maximum tolerated dose revealed no significant impact on fertility.
In patients whose disease is insufficiently controlled with the maximum tolerated dose of metformin taken alone;
Larotrectinib was negative in the in vivo mouse micronucleus test at the maximum tolerated dose of 500 mg/kg.
the effective dose predicted from preclinical studies being substantially higher than the observed human maximum tolerated dose.
Of them started treatment with carvedilol, and the remaining 45- with bisoprolol, with gradual titration to the maximum tolerated dose, which was 26.5± 21.1 mg daily for carvedilol and 5.8± 3.0 mg daily for bisoprolol.
an intrathecal dose of 35 mg was identified as the maximum tolerated dose.
2.5 mg of amlodipine once a day, and increase cautiously and progressively to the maximum tolerated dose.
Glimepiride 4 mg/day; Metformin(immediate- or extended-release formulations)≥1500 mg/day plus maximum tolerated dose, which must be at least half maximum dose, of a sulphonylurea for at least 8 weeks prior to enrolment.
Based on the dose-limiting toxicity of myelosuppression, the maximum tolerated dose(MTD) was established at 2.0 mg/m2day with G-CSF and 1.4 mg/m2/day without G-CSF in a pharmacokinetic study
levels are not adequately controlled with the maximum tolerated doses of the other medicines.
the maximum recommended human dose of 2 grams on a mg/m basis, and represent the maximum tolerated doses in these species.
Metformin(immediate- or extended-release formulations)≥1500 mg/day plus maximum tolerated dose, which must be at least half maximum dose, of a sulphonylurea for at least 8 weeks prior to enrolment.
rabbits at doses near the maximum tolerated dose and/or maternally toxic doses showed reproductive(embryotoxicity in rats,
decrease systemic opioid use over a sustained period of time for patients whose pain was inadequately controlled with their maximum tolerated dose of IT ziconotide(median 8.7 μg/day,
receiving the same monotherapy dose of 30 mg/m2 twice daily(the maximum tolerated dose for monotherapy)
Have you done maximum tolerated dose studies?
The compound does not appear to have been tested up to the maximum tolerated dose.