Examples of using Tipranavir in English and their translations into Hungarian
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APTIVUS may be less effective due to decreased tipranavir plasma concentrations in patients taking these agents concomitantly.
However a decrease of colchicine concentrations cannot be excluded since both tipranavir and ritonavir exhibit inducing potential towards CYP3A and P-gp.
Based on theoretical considerations, tipranavir or ritonavir concentrations might increase upon co-administration with itraconazole or ketoconazole.
Co-administration of Harvoni with tipranavir(ritonavir boosted)
was co-administered with 20 ml of aluminium- and magnesium-based liquid antacid, tipranavir AUC12h, Cmax
An increase in gastric pH that may result from H2-receptor antagonist therapy is not expected to have an impact on tipranavir plasma concentrations.
Concomitant use of boosted saquinavir and tipranavir, co-administered with low dose ritonavir in a dual-boosted regimen,
Tipranavir should be used during pregnancy only if the potential benefit justifies the potential risk to the foetus.
Tipranavir, co-administered with low dose ritonavir has been studied in a total of 6308 HIV-positive adults as combination therapy in clinical studies,
Hence tipranavir at therapeutic dose with low dose of ritonavir did not prolong the QTc interval
Co-administration of valaciclovir, tipranavir and low dose ritonavir was not associated with clinically relevant pharmacokinetic effects.
saquinavir, tipranavir(antiretrovirals used to treat HIV);
Therefore, the co-administration of boosted saquinavir and tipranavir, co-administered with low dose ritonavir, is not recommended.
Mean decrease in viral load from baseline to week 48, according to tipranavir baseline mutation score
Clinical isolates that exhibited a≥ 10-fold decrease in tipranavir susceptibility harboured eight or more tipranavir-associated mutations.
This score counting the 16 amino acids that have been associated with reduced tipranavir susceptibility and/ or reduced viral load response.
nelfinavir, tipranavir, saquinavir and atazanavir.
saquinavir, tipranavir, lopinavir/ritonavir) are contraindicated(see section 4.3).
nevirapine, tipranavir or HIV known to be resistant to integrase inhibitors.
Based on theoretical considerations, tipranavir, co-administered with low dose ritonavir, is expected to increase cisapride concentrations.

