Early data suggest that mucosal or acral melanomas with activating mutations or amplifications in c-KIT may be sensitive to a variety of c-KIT inhibitors.
Data from Study 5 suggest that the beneficial treatment effects were largely limited to patients with the highest level of HER2 protein overexpression(3+)(see Table 12).
Smaller businesses still face difficulties in obtaining credit, but surveys of both banks and borrowers indicate that conditions are slowly improving for those firms as well.
Previous work has highlighted a shortfall of molybdenum(a trace metal necessary for eukaryotic and nitrogen-fixing bacterial life) in the Precambrian oceans, which implies that the evolution and diversification of many organisms was delayed.
A drought-severity record reveals three distinct trends, and suggests that greenhouse gasses and, potentially, aerosols generated by human activity may affect drought risk.
Also added text to state that only 12% of the men had nonpalpable T1x tumors, suggesting that a minority of tumors were detected by PSA screening, whereas the majority were clinically detected.
Genetic analysis of wild and domestic Large White pigs from Europe and Asia suggests that early nineteenth century farmers imported Chinese pigs into Europe to improve the quality of their own breeds.
Recent data support the idea that movements play a crucial role in letter representation and suggest that handwriting knowledge contributes to visual recognition of letters.
A large body of data supports the view that movement plays a crucial role in letter representation and suggests that handwriting contributes to the visual recognition of letters.
Previous research which has attempted to calculate the carbon footprint of the industry suggested that tourism was responsible for 2.5- 3% of global greenhouse gas emissions.
The levels of the cardiac specific cell-free DNA marker are strongly increased in the plasma of septic patients, suggesting that massive cardiomyocyte death occurs in these subjects.
The most recent trend data from the National Committee for Quality Assurance suggest that mammography screening rates have increased among women in all insurance categories since the USPSTF's 2009 recommendation(62).
A comparison of model simulations that included and excluded human-induced warming also suggests that Southern Alps glacier ice changes between 1980 and 2005 partly reflects man-made climate change.
However, the study also shows that saliva of infected animals is not sufficient to transmit the virus to naive animals, suggesting that contact transmission occurs through other body fluids.
A few retrospective(case-control) studies reported in the mid-1990s suggested that induced abortion(the deliberate ending of a pregnancy) was associated with an increased risk of breast cancer.
Furthermore, several studies suggest that the use of liposomes is not associated with autoimmune responses, toxicity or gonadal localization after systemic delivery(Mori& Fukatsu, 1992).
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